The short answer
The Zalarma investor database, as of 2026-11-01 lists 2,036 startup-investor records in the 12 Midwest states. Illinois has 1,033, followed by Ohio, Michigan, Missouri and Minnesota; 534 list pre-seed. Healthcare is the focus of 40% of sector-tagged Midwest investors, versus 33% nationally.
- 2,036 Midwest startup-investor records; 1,033 in Illinois.
- Cleveland, St. Louis, Minneapolis, Columbus, Detroit and Cincinnati each have 50+ investor records.
- Healthcare: 40% of Midwest investors vs 33% nationally.
- Family offices are 31% of Midwest records.
- Median check range $150K to $1.6M.
Key findings
- 2,036 US startup-investor records in our database are based in the 12 Midwest states, 7.0% of the 28,944 US startup-investor records with a known state.
- Illinois holds 1,033 of them (51%), most in Chicago. Ohio (278), Michigan (193), Missouri (152) and Minnesota (134) follow.
- 534 Midwest investors list pre-seed and 1,197 list seed.
- The Midwest leans toward healthcare: 40% of sector-tagged Midwest investors list it, against 33% nationally. Education technology (15% vs 8.5%) and manufacturing (7.6% vs 4.0%) are over-represented too.
- Family offices are 621 of the region's records (31%), the second-largest group after venture firms and partners.
Why a Midwest report
Founders in Columbus, St. Louis, Minneapolis or Indianapolis hear two stories: that there is no capital in the Midwest, or that everything is in Chicago. Neither is quite right. The Zalarma investor database, as of 2026-11-01 lists 2,036 startup-investor records across the region, spread over a dozen cities with real investor benches. This report shows where they are, what they fund and how much they write, so you can build a list that starts close to home.
Startup investors by Midwest state
Startup investors by Midwest state
| State | Startup investors | Pre-seed | Seed | Angels | Family offices |
|---|---|---|---|---|---|
| Illinois | 1,033 | 280 | 592 | 183 | 346 |
| Ohio | 278 | 67 | 177 | 81 | 77 |
| Michigan | 193 | 69 | 131 | 68 | 43 |
| Missouri | 152 | 26 | 83 | 20 | 31 |
| Minnesota | 134 | 32 | 73 | 20 | 47 |
| Indiana | 72 | 25 | 56 | 19 | under 10 |
| Wisconsin | 64 | 11 | 38 | under 10 | 19 |
| Kansas | 34 | under 10 | under 10 | under 10 | 21 |
| Iowa | 28 | under 10 | 21 | under 10 | under 10 |
| Nebraska | 25 | 10 | 13 | under 10 | 11 |
| North Dakota | 12 | under 10 | under 10 | under 10 | under 10 |
| South Dakota | 11 | under 10 | under 10 | under 10 | under 10 |
"Under 10" means the count is too small to publish. Illinois dominates the totals, but Ohio, Michigan, Missouri and Minnesota each have well over 100 startup-investor records. Ohio's investors are spread across three cities: Cleveland (84), Columbus (67) and Cincinnati (59).
Cities with the most investors
| City | Startup investors |
|---|---|
| Chicago | 899 |
| Cleveland | 84 |
| St. Louis | 79 |
| Minneapolis | 74 |
| Columbus | 67 |
| Detroit | 64 |
| Cincinnati | 59 |
| Indianapolis | 41 |
| Ann Arbor | 37 |
| Kansas City | 24 |
| Grand Rapids | 17 |
| Madison | 14 |
| Wayzata | 12 |
| Oak Brook | 12 |
| Des Moines | 11 |
Beyond Chicago (899), the deepest benches are in Cleveland (84), St. Louis (79), Minneapolis (74), Columbus (67), Detroit (64) and Cincinnati (59). Ann Arbor (37) punches above its size. See the metro pages for Chicago, Minneapolis and Detroit.
What Midwest investors fund
Share is of Midwest startup investors who list at least one sector (1,276), next to the same share for the whole US. Investors often list several sectors.
| Sector | Midwest investors | Midwest share | US share |
|---|---|---|---|
| B2B SaaS & enterprise software | 734 | 58% | 60% |
| Consumer & retail | 629 | 49% | 51% |
| Healthcare & digital health | 515 | 40% | 33% |
| Fintech | 411 | 32% | 33% |
| Biotech & life sciences | 287 | 22% | 20% |
| Deep tech & hardware | 284 | 22% | 24% |
| Machine learning & data | 234 | 18% | 26% |
| Climate & energy | 224 | 18% | 16% |
| Education technology | 187 | 15% | 8.5% |
| Manufacturing & industrial | 97 | 7.6% | 4.0% |
Midwest investors by sector focus (top 10)
Software and consumer lead, as they do nationally. The difference is in the next tier: healthcare, education technology and manufacturing are a larger share of the Midwest investor base than of the US as a whole, while machine learning and data is smaller (18% vs 26%). If you build in health, learning or industry, the region's investors are more likely to know your customers.
Who invests: types, stages and checks
| Investor type | Midwest records |
|---|---|
| Angels & syndicates | 402 |
| Venture capital firms & partners | 1,083 |
| Micro-VCs | 26 |
| Family offices | 621 |
| Corporate VCs | 42 |
| Accelerators | 16 |
- Stages listed: pre-seed 534, seed 1,197, Series A 758, Series B and later 436.
- Median check range: $150K to $1.6M, a lower ceiling than the US median for startup investors ($150K to $3M).
- Check bands by minimum (1,317 with a stated check): under $50K 121; $50K–$250K 611; $250K–$1M 281; $1M+ 304.
Firms with the most investor records in the region
Firms with the most Midwest-based investor records that list a stage (records in brackets): Thompson Street Capital Partners (18), Cultivation Capital (14), Baird Capital (13), Monroe Capital LLC (11). Others with several records include Corazon Capital, Drive Capital, Madison Dearborn Partners, LLC, CincyTech USA, Center Rock Capital Partners, LP, Rev1 Ventures. The list mixes early-stage venture funds, regional programs such as CincyTech and Rev1 Ventures, and growth and private-equity firms that list later stages, so check each firm's stage before you pitch.
What to do with this
- Raise in your own state first. A local lead makes Chicago and coastal investors easier to win later.
- Treat the region as one market. A Columbus founder can reasonably pitch Cincinnati, Cleveland, Pittsburgh and Indianapolis investors; most are a short drive or flight away.
- Do not skip family offices. At 31% of Midwest records they are a major source of capital, usually reached through a warm intro.
- Lead with your sector if it is a regional strength. Healthcare, edtech and manufacturing founders have a deeper local bench than the national averages suggest.
State lists: Illinois, Ohio, Michigan, Missouri, Minnesota.
Methods note
Data: Zalarma investor database, as of 2026-11-01. The Midwest here is the 12 states in the US Census Bureau's Midwest region: Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota and Wisconsin. Records are US startup investors (angels, venture firms and partners, micro-VCs, family offices, corporate VCs and accelerators) with a state in the region; one record can carry several types, stages and sectors. Sector shares use as the base the records that list at least one sector. Cities are as recorded on each record. Firm counts are the number of investor records tied to that firm. Counts under 10 are suppressed. These are records in our database, not a census of every Midwest investor.
Frequently asked questions
How many startup investors are in the Midwest?
Our database lists 2,036 startup-investor records in the 12 Census Midwest states. That is records in our database, not every investor in the region.
Which Midwest cities have the most startup investors?
Chicago (899), then Cleveland (84), St. Louis (79), Minneapolis (74) and Columbus (67).
Is there pre-seed capital in the Midwest?
Yes. 534 Midwest startup investors in our data list pre-seed, and 1,197 list seed.
What sectors do Midwest investors focus on?
Software and consumer lead. Healthcare, education technology and manufacturing make up a larger share of Midwest investors than of US investors overall.