The short answer
Our database lists 102 startup investors in North Carolina focused on healthcare & digital health — 26% of the 396 startup investors we list in the state. Most are in Raleigh (30), Durham (20), Charlotte (12). (Zalarma investor database, as of 2026-11-01.)
What these investors look for
- Lead with the regulatory path. Healthcare investors want to see that you know whether you are a device, software as a medical device, a service, or a lab test, and what clearance (if any) you need before revenue.
- Name your buyer precisely: health system, payer, employer, provider group or patient. The sale cycle you describe tells an investor how much runway you really need.
- Clinical advisors and pilot sites count as traction at pre-seed. A signed pilot letter from a regional hospital often matters more than a famous name on the cap table.
Where they are
| City | Investors |
|---|---|
| Raleigh | 30 |
| Durham | 20 |
| Charlotte | 12 |
| Chapel Hill | 11 |
What stages they back
Of the 102 records in this group that list a stage, here is how many invest at each one (investors often list several).
Investors by stage
Who they are
The mix of investor types tells you where your first checks are most likely to come from.
Investors by type
Sectors they focus on
Sector focus as listed on each record. Generalists who list many sectors are counted in each.
Investors by sector focus
Typical check sizes
Based on the 102 records that list a check size (we use the low end of a stated range).
Investors by typical check size
Firms with the most of these investors in North Carolina
Firms ranked by how many of their investors in this slice appear in our database with a stage listed. A starting map, not a ranking of quality.
| Firm | Main stages | Listed |
|---|---|---|
| Plexus Capital, LLC | Seed, Series A, Series B+ | 15 |
| Wolfpack Investor Network | Pre-seed, Seed | under 10 |
| Hatteras Venture Partners | Seed, Series A | under 10 |
| VentureSouth | Seed, Series A | under 10 |
| Bull City Venture Partners | Seed, Series A | under 10 |
| Morgan Creek Capital Management, LLC | Seed, Series A, Series B+ | under 10 |
| SJF Ventures | Seed, Series A | under 10 |
Next steps
- See all startup investors in North Carolina.
- Compare with Healthcare & digital health nationally.
- Plan your outreach with the warm intro playbook.
About this data
Counts are records in the Zalarma investor database, as of 2026-11-01: angels, venture firms and their partners, micro-VCs, family offices, corporate VCs and accelerators that list startup investing. One investor can appear in several stage or sector rows. Stage, sector and check size come from what each record lists, so not every record has every field. Counts under 10 are not shown. Firm names are listed; we do not publish personal contact details on this site. Read how we build and check the data.
Frequently asked questions
How many healthcare & digital health investors are in North Carolina?
The Zalarma investor database lists 102 startup investors in North Carolina focused on healthcare & digital health, as of 2026-11-01.
Where in North Carolina are they?
In our data: Raleigh (30), Durham (20), Charlotte (12), Chapel Hill (11).
How do I reach them?
Shortlist the investors whose check size and focus fit your round, look for a warm path through founders they backed or local angel groups, and send a short, specific note to the rest. Zalarma can build the shortlist for you.